Identification of complex models of type 2 diabetes from IVGTT data by model-based design of experiments

Federico Galvanin1, Massimiliano Barolo1, Riccardo C. Bonadonna2 and Fabrizio Bezzo1,    1CAPE-Lab, Department of Industrial Engineering, University of Padova, via Marzolo 9, I-35131, Padova, Italy, 2Department of Medicine, Division of Endocrinology and Metabolic Diseases, University of Verona, Piazzale Stefani 1, I-37126, Verona, Italy, E-mail: federico.galvanin@unipd.it

Abstract

Intravenous glucose tolerance tests (IVGTTs) are typically used to assess insulin resistance and insulin secretion activities in subjects affected by type 2 diabetes by adopting minimal models. However, the amount of information that can be obtained from IVGTTs ...

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