23rd European Symposium on Computer Aided Process Engineering

Identification of complex models of type 2 diabetes from IVGTT data by model-based design of experiments

Federico Galvanin¹,^∗ Massimiliano Barolo¹, Riccardo C. Bonadonna² and Fabrizio Bezzo¹,    ¹CAPE-Lab, Department of Industrial Engineering, University of Padova, via Marzolo 9, I-35131, Padova, Italy, ²Department of Medicine, Division of Endocrinology and Metabolic Diseases, University of Verona, Piazzale Stefani 1, I-37126, Verona, Italy, ^∗E-mail: [e-mail]

Abstract

Intravenous glucose tolerance tests (IVGTTs) are typically used to assess insulin resistance and insulin secretion activities in subjects affected by type 2 diabetes by adopting minimal models. However, the amount of information that can be obtained from IVGTTs ...