Chapter 15: Computing Power and Sample Size

Introduction

Computing Sample Size for a t Test

Calculating the Sample Size for a Test of Proportions

Computing Sample Size for a One-Way ANOVA Design

Conclusion

Chapter 15 Exercises

Introduction

In my 26 years as a biostatistician at the Rutgers Robert Wood Johnson Medical School in New Jersey, the question I was most frequently asked was, “I’m doing an experiment; how many subjects do I need?” Just about any study, especially one for which you are asking for funding or applying for a grant, will require detailed power and sample size calculations.

As discussed in Chapter 1, the power of a study is the probability that the study will result in a statistically significant finding if the drug or treatment ...

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