
Example: Gene Expression Analysis for Alternative Indications ◾ 171
e highlighting in Figure16.5 indicates which disease gene combi-
nations are signicant given the overall occurrence of the gene and the
disease in the patient population in all of NCBI GEO, using a chi-squared
test and ensuring that the actual value is greater than the expected value.
Clearly we nd the known correlation to breast cancer cells, but there ...