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Chapter 17
Example: Side Effects
D
engineered to treat disease or the symp-
toms of disease. But the molecules that we ingest as drugs frequently
do more than one thing. Some of these additional things are side eects.
When engineering a new drug, it helps to be aware of what side eects
are taking place for those related drugs currently on the market or in
clinical trials. is knowledge can help the drug designer avoid chemical
signatures or o-target eects that may cause problems when the drug is
administered to a large patient population.
We begin with a search against Medline to nd abstracts containing
references to ...