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Accelerating Discovery
book

Accelerating Discovery

by Scott Spangler
September 2015
Intermediate to advanced content levelIntermediate to advanced
292 pages
8h 43m
English
Chapman and Hall/CRC
Content preview from Accelerating Discovery
246 Accele rating D iscover y
Using this approach, we created a graph of all the kinases and then col-
ored them by known P53 associations. e result was immediately striking.
e known P53 kinases were occurring together and the other kinases were
mostly in other areas of the kinase tree. Moreover, there were a few kinases not
known to be P53 kinases that seemed to be in among those that were known.
is was exactly what we hoped to nd, because it gave us a ready list of poten-
tial candidate kinases on which to begin running experiments (Figure22.3).
In order to validate that our predictions were reasonable, we needed to nd
a way to test ...
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Publisher Resources

ISBN: 9781482239140