Top-Down Versus Bottom-Up

Although times were simpler when Mendel was tending his garden of Pisum sativum in the 1860s, the scientific method used by the father of genetics is virtually identical to that used by a contemporary molecular biologist. There is the formation of a hypothesis followed by observation and controlled, documented experiments that produce results. These data are in turn interpreted to determine whether they support or refute the hypothesis. Regardless of whether the experiments focus on the color of pea plant petals in a monastery garden or on the results of a microarray assay performed on a murder suspect's DNA, data are generated, and they must be accurately recorded for interpretation and future reference.

Mendel recorded ...

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