Even with all of the public-domain databases accessible through the Internet, there will be research tasks that necessitate using a local database. The reasons vary from a need to collect, analyze, and publish sequence information inside a small laboratory to establishing a massive data warehouse as part of a pharmacogenomic R&D effort. In either case, the general issues and challenges are the same, albeit in different degrees of severity. As shown in Table 2-7, the major database implementation issues range from the storage capacity requirements and cost to scalability and security.

Table 2-7. Bioinformatics Database Implementation Issues.
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