Tool Selection

An arbitrary decision to use median spot fluorescence intensity instead of a mean or mode measurement, for example, can drastically alter gene expression analysis. Ideally, the selection of a statistical method reflects the researcher's knowledge of the underlying biological principles as well as the inherent limitations of the statistical methods used to analyze the data. Researchers typically consider the statistical methods used when determining whether the data from a particular experiment is valuable to them.

With the proliferation of multifunction calculators, dedicated statistical analysis software packages (see Table 6-4), and statistical analysis available through general-purpose database and spreadsheet programs, it's ...

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