O'Reilly logo

Bioinformatics with R Cookbook by Paurush Praveen Sinha

Stay ahead with the world's most comprehensive technology and business learning platform.

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, tutorials, and more.

Start Free Trial

No credit card required

Pairwise sequence alignment

As mentioned in the introductory section of this chapter, while analyzing genes or proteins sequences, we often need to compare them to know their similarities and differences. This serves the purposes from various perspectives, such as for evolutionary studies and to understand the structure and function of a novel sequence by comparing it to the known one. To know whether the two gene/protein sequences we are studying are similar or different at the quantitative level, we measure their similarities.

Before making comparative statements about two sequences, we have to produce a pairwise sequence alignment. Pairwise alignment refers to the optimal way of arranging two sequences in order to identify regions of similarity ...

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, interactive tutorials, and more.

Start Free Trial

No credit card required