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Bead array technologies for genetic disease screening and microbial detection

S.A. Dunbar and S.V. Angeloni,    Luminex Corporation, USA

Abstract:

In recent decades rapid development and utilization of whole genome assay technologies has produced a vast amount of information on the gene expression patterns and genomic sequences of a number of different organisms. However, once a whole genome assay is used to identify key markers, faster and more cost-effective methods are more practical for the analysis of larger numbers of samples. Midplex or mid-density arrays provide a pragmatic solution for high-throughput analysis of hundreds to thousands of samples where only dozens to a few hundred markers need to be followed. This chapter describes ...

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