Electrophoretic approaches to sample collection and preparation for nucleic acids analysis

C. Bradburne,    Johns Hopkins University, USA


Gel electrophoresis has been an integral part of molecular biology labs for decades, finding utility in analysis, separation, molecular engineering and clean-up of nucleic acids. It continues to be refined, and emerging technologies are allowing fine control of DNA and RNA in a gel. One of these technologies, SCODAphoresis, even provides superior separation from common inhibitors such as soil humic acids, enabling DNA extraction and analysis from previously un-extractable sample matrices. The electrophoretic sample separation of nucleic acids will continue to be an important part of the sample-to-answer ...

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