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Electrophoretic approaches to sample collection and preparation for nucleic acids analysis

C. Bradburne,    Johns Hopkins University, USA

Abstract:

Gel electrophoresis has been an integral part of molecular biology labs for decades, finding utility in analysis, separation, molecular engineering and clean-up of nucleic acids. It continues to be refined, and emerging technologies are allowing fine control of DNA and RNA in a gel. One of these technologies, SCODAphoresis, even provides superior separation from common inhibitors such as soil humic acids, enabling DNA extraction and analysis from previously un-extractable sample matrices. The electrophoretic sample separation of nucleic acids will continue to be an important part of the sample-to-answer ...

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