The oxygen transfer rate and overall volumetric oxygen transfer coefficient


During aerobic microbial growth, oxygen is required by microorganisms as a final electron acceptor for energy production during oxidative phosphorylation (Section 5.1.2). Should the oxygen in the culture decrease below that sufficient for oxidative phosphorylation, the metabolism of the organism will be limited by the oxygen concentration and the specific growth rate will decrease according to the Monod Model (Equation 7.6). In this manner cell growth and product formation will become transport rather than kinetically controlled, leading to a decline in the yield and productivity of the process.Provision of adequate oxygen is especially challenging because ...

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