
468 Biosensors Based on Nanomaterials and Nanodevices
Plasma
Spiked with standard proteins
Unspiked fresh blood
Whole blood
PSA
Plasminogen
CRP
C3
Control
TNF–α
Control
IL–10
IL–6
IL–1β
FIGURE 18.12
(a) Optical micrographs show the effective separation of plasma from fresh whole blood. (b) IBBC for the rapid
measurement of a panel of serum biomarkers from a ngerprick of whole blood. (Reprinted from Fan, R. et al.,
Nat. Biotechnol., 26(12), 1373, 2008. With permission.)
E. coli
P. aeruginosa
S. aureus
C. albicans +
hybridization control (Cy3)
Spotting control (Cy3)
template for Cy5 multiplex PCR
P. aeruginosa
S. aureus
(a)
Large reservoirs
150 µL