51Quantum Dots for Bioimaging
The direct adsorption of biomolecules on nanomaterials is fast and easy to perform fol-
lowing conventional adsorption techniques.
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Adsorption results from hydrophobic inter-
action or electrostatic interaction between the biomolecules and the nanoparticle surface.
It has been used for the detection of specic nucleic acid (NA) sequences that has impor-
tant applications in medical research and diagnosis.
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In most cases, specic
sequences are identied through the hybridization of an immobilized probe that is com-
plementary to the target NA after the latter has been modied with a covalently linked
uorescent or enzyme label.
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3.3.2 Covalent Binding
The alternative way to a ...