61Quantum Dots for Bioimaging
unique properties of these NMs indicates a possible ultrasensitive nanoscale detection of a
cell and its components. This requires a proper interfacing of biological recognition probes
with the surface-modied NMs such as QDs, which can provide excellent solutions to meet
biointerfacing requirements, owing to their tailorable physical and chemical properties by
varying size, composition, and shape at the nanoscale.
3,158,159
NPs are very effective in the
sensing of whole cells that include human cells and bacterial cells for in vitro diagnosis
because of their nanoscale dimensions.
Semiconductor QDs have been used to detect whole cancer cells that overexpress HER2,
a surface-coating protein that is found in brea ...