
103Graphene-Based Optical Biosensors and Imaging
researchers have also successfully employed a similar strategy for reducing and function-
alizing GO as the drug delivery carrier and the imaging agent. Guo et al. have used her-
ceptin, an antibody against the Her2 receptor, as the reducing and functionalizing reagent
to prepare a new functional reduced GO in one step.
50
The obtained herceptin-rGO has
low cytotoxicity and excellent solubility in buffer and cell culture media. In addition,
the herceptin-functionalized rGO has a unique two-photo excitation photoluminescence
property and can be readily uptaken by cells for two-photo excitation imagi ...