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7
In Vivo Biodetection Using Surface-Enhanced
Raman Spectroscopy
Seunghyun Lee, Ulhas S. Kadam, Ana Paula Craig, and Joseph Irudayaraj
7.1 Introduction
Nanophotonics engages with light–material interaction behaviors that occur on wave-
length or subwavelength scales, where the electromagnetic eld is conned to the sur-
face of designed nanostructures with unique and tunable optical properties. In particular,
“plasmonics” using surface plasmon polaritons (SPPs), simply called surface plasmon,
is diverse and a rapidly growing eld in nanophotonics. Over the recent decades, the emer-
gence of novel nanomaterials and fabrication of diverse nanost