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Biosensors Based on Nanomaterials and Nanodevices
book

Biosensors Based on Nanomaterials and Nanodevices

by Jun Li, Nianqiang Wu
December 2017
Intermediate to advanced content levelIntermediate to advanced
517 pages
21h 5m
English
CRC Press
Content preview from Biosensors Based on Nanomaterials and Nanodevices
219Nanomaterial-Based Electrochemiluminescence Biosensors
probes for the detection of kinase activity (Xu et al. 2010). The nanoparticles were conju-
gated specically to the thiophosphate group after the protein phosphorylation process,
amplied the ECL signal of luminol, and thus offered a highly sensitive ECL biosensor
for kinase activity detection.
AuNPs were further used as ECL emitter carrier for the fabrication of highly sensitive
ECL biosensors. For example, Zhang’s group developed a highly sensitive ECL method
for the detection of DNA hybridization event using AuNPs as a carrier for ECL label and
ssDNA (Wang et al. 2006). Due to multiple signal reporters per hybridization event, a detec-
tion limit of as low as 5 pM for target ssDNA
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Publisher Resources

ISBN: 9781466551527