229Nanomaterial-Based Electrochemiluminescence Biosensors
Ru(bpy)
3
2+
serves as a ECL marker, and Fe
3
O
4
nanoparticles allow external manipulation
by a magnetic eld. This ECL sensor shows a wide linear range, high sensitivity, and good
stability. In the work of Lee et al. (Lyu et al. 2009) monodispersed MNPs were coated with
poly(3-thiopheneacetic acid) via an oxidative polymerization using KMnO
4
as an oxidant,
and the magnetic eld–driven multilayer lms of the functional MNPs were formed as
a matrix for immobilization of Ru(bpy)
3
2+
. This ECL sensor exhibited quite a low limit of
detection for TPA and also showed good reproducibility.
Recently, Jie et al. prepared a novel magnetic Fe
3
O
4
-CdSe composite QD and success-
fully applied to sensitiv ...