
374 Biosensors Based on Nanomaterials and Nanodevices
surface plays an important role in dening sensitivity of nanobiosensors. These indicate
that care must be taken to precisely control the functionalization chemistry to make full
use of the sensor capability.
15.1.2.3 Sensing Environment
Many of the biosensing experiments have been carried out with the sensors and mol-
ecules submerged in a liquid environment. This is useful not only for eliminating wash-
ing and drying steps necessary for measurements done in air (dry sensing) but also for
acquiring direct, real-time information, such as kinetics, from the biomolecules interacting
with the sen ...