
384 Biosensors Based on Nanomaterials and Nanodevices
In order to understand how calibrating by dI
ds
/dV
g
suppresses variations in the sens-
ing response between different sensors, it is helpful to revisit the physics of the sensing
mechanism in more detail. Ishikawa et al. demonstrated several experiments using biotin/
streptavidin binding to pinpoint the most likely cause of NW sensor signal.
63
The In
2
O
3
NW sensors in these experiments were fabricated and functionalized following a previ-
ously developed procedure,
24,25,84
and biotin was then anchored on the In
2
O
3
NW surface.
Interdigitated source and drain electrodes were introduced to decrea ...