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17
Solid–Liquid Phase Change Nanoparticles
as Thermally Addressable Biosensors
Chaoming Wang, Yan Hong, Liyuan Ma, and Ming Su
17.1 Introduction
A challenge of turning molecular biology knowledge into advance in disease detection to
benet patients is that most of available biomarkers are not powerful, lacking either sensi-
tivity or specicity. Parallel to the effort of nding more specic biomarkers, one feasible
way of providing better predictive value is to detect multiple low specicity biomarkers,
and collectively analyze the response of multiple biomarkers contained in a sample.
1–5
The
multiplexed detection can enhance the reliability a ...