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18
Microfluidic and Lab-on-Chip
Technologies for Biosensors
Yuxin Liu and Xiang Li
18.1 Introduction and Overview of Microfluidics and Sensor Integration
Biological or biochemical sensing and quantication are of critical importance for medi-
cal, biological, chemical, and biotechnological applications. Biosensor represents a device
that can detect and measure a specic biological organism (i.e., cells, proteins, enzymes,
or nucleic acids) in a biological or biochemical process with a large variety of samples
including body uids, food samples, cell cultures, and environmental samples. The sens-
ing ability relies on one or more sensing mecha