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Biotechnology and Infectious Diseases by Brooke A. Jude

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            CHAPTER 5            

BIOTECHNOLOGY AND VACCINE DEVELOPMENT

Vaccines.gov defines a vaccine as “a product that produces immunity from a disease in a susceptible organism.” Vaccination is the practice of inoculating healthy individuals with attenuated1 or related (nonpathogenic) microorganisms, or their antigenic products. This assault is administered to elicit a response by the host adaptive immune system that will protect against later infection by the corresponding pathogen (Flint, Enquist, and Racaniello 2008). This practice was introduced to the modern world by Jenner in the late 18th century as a method to prevent smallpox infections (Lombard, Pastoret, and Moulin 2007; Fenner et al. 1988). Different and distinct from therapies ...

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