
187
8
Micropatterning
Techniques to Control
Cell–Biomaterial
Interface for Cardiac
Tissue Engineering
Harpinder Saini, Feba S. Sam,
Mahshid Kharaziha, and Mehdi Nikkhah
Abstract: Recent advancements in microengineering technologies have
enabled creating biomimetic invitro tissue substitutes for the repair and regen-
eration of injured myocardium. In this chapter, we will broadly overview the
applications of micropatterning techniques in cardiac tissue engineering.
We will rst describe the cellular organization, microarchitecture, and the
fundamentals of cell–matrix interactions within the native myocardium. Our
discussion will be followed by a ...