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Coffee in Health and Disease Prevention by Victor R. Preedy

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Chapter 23

Coffee and Hippuric Acid

Masanori Ogawa     Health Service Center, Jichi Medical University, Shimotsuke, Tochigi, Japan

Abstract

It has been reported that coffee intake results in an elevation of hippuric acid (HA) concentration in urine. Among the phenolic compounds in coffee, chlorogenic acid (CGA) is a major substance, metabolized to HA in the human body. In the metabolism of CGA, the colonic microflora play an important role, and there is large inter-individual variation. CGA works as a strong antioxidant and has been shown to have various beneficial properties in vitro. The antioxidant activity of CGA in vivo is uncertain; however, the benefits of CGA in humans and animals have been studied. The antioxidant activity of coffee depends ...

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