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Coffee in Health and Disease Prevention by Victor R. Preedy

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Chapter 79

Potential Effects of Chlorogenic Acids on Platelet Activation

Jae B. Park     Diet, Genomics, and Immunology Laboratory, Beltsville, MD, USA

Abstract

Coffee is a most consumed beverage worldwide, and has been reported to have positive health effects on several chronic diseases, including cardiovascular diseases (CVD). Atherosclerosis is an inflammatory cardiovascular disease, frequently associated with plaque formation/ruptures, and platelet activation and repairing events. Although platelet activation is a necessary step, the hyperactivation of platelets often aggravates enduring CVD conditions such as atherosclerosis, acute coronary syndrome, angina, and acute myocardial infarction. Chlorogenic acids (CHAs) are phytochemicals abundantly ...

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