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Coffee in Health and Disease Prevention by Victor R. Preedy

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Chapter 81

Caffeolyquinic Acid Protects against Alzheimer’s Disease through Inhibition of Amyloid Beta-Induced Toxicity

Junkyu Han1, Abdelfatteh El Omri2, Kazunori Sasaki2,  and Hiroko Isoda1     1Faculty of Life and Environmental Sciences, Alliance for Research on North Africa (ARENA), University of Tsukuba, Tsukuba City, Ibaraki, Japan     2Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba City, Ibaraki, Japan

Abstract

Although several drugs for Alzheimer's disease are now available, none of them are able to slow down, halt, or cure the neurodegeneration in Alzheimer's disease. In this respect, inhibition of amyloid beta (Aβ) aggregation is becoming an attractive pharmacological therapeutic strategy. Some research has demonstrated ...

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