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Coffee in Health and Disease Prevention by Victor R. Preedy

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Chapter 86

Chlorogenic Acid in Whole Body and Tissue-Specific Glucose Regulation

Jasmine M. Tunnicliffe1, Theresa Cowan1,  and Jane Shearer1,2     1Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada     2Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada

Abstract

Chlorogenic acids (CGA) are a predominant class of phenolic acids found in coffee. CGA have substantial biological activities and may be responsible for the beneficial effects of coffee on glucose regulation and the development of type 2 diabetes. This chapter reviews the impact of CGA on whole body and tissue specific glucose regulation. Upon consumption, small amounts of CGA are absorbed in the small intestine where it ...

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