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Coffee in Health and Disease Prevention by Victor R. Preedy

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Chapter 97

The Chemistry of Coffee Furans and Hydroxycinnamates under Simulated Gastric Conditions

Implications for Bioactivity and Bioavailability

Alessandra Napolitano,  and Lucia Panzella     Department of Chemical Sciences, University of Naples Federico II, Complesso MS Angelo, Naples, Italy

Abstract

The health benefit effects associated with the consumption of coffee beverages are at least in part attributable to the chemopreventive action exerted by components like phenols, particularly hydroxycinnamates, and furan diterpenes. In the acidic environment of the stomach, dietary and endogenous nitrite ions are converted into a series of nitrosating/nitrating species capable of triggering major events implicated in mutagenesis and carcinogenesis. ...

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