496 Computational Modelling of Biomechanics and Biotribology
consisting of a system of nonlinear partial differential equations describ-
ing the spatio-temporal evolution of concentrations and densities of the
cell types, extracellular matrix types and growth factors needed for the
healing process. They described cell migration using not only haptokinetic,
but also chemotactic and haptotactic in uences and they hypothesized cell
differentiation to be controlled by the presence of growth factors and suf-
cient vascularization.
16.3 Applications of finite element modelling (FEM)
and computational mechanobiology to bone
tissue engineering
A large number of factors are involved in the design of scaffolds for bone
tissue engineering: the ...