For cell poker experiments the response of an adherent cell to creep inden-
tation is given as (Koay et al ., 2003) (Fig. 4.9):
δ
t
F
Rk
k
kk
eH
τ
I
t
(
)
=
⎛
⎝
⎝
⎝
⎞
⎠
⎟
⎞
⎞
⎠
⎠
⎡
⎣
⎢
⎡
⎡
⎣
⎣
⎤
⎦
⎥
⎤
⎤
⎦
⎦
−
8
11
k
+
−
⎛
⎝
⎜
⎛
⎛
⎝
⎝
1
1
12
k
()
t
[4.21]
Both the linear-elastic and linear-viscoelastic solid models have been used
to determine the material properties of chondrocytes (Guilak et al ., 2000;
Trickey et al ., 2000; Leipzig and Athanasiou, 2005), endothelial cells (Ther ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month, and much more.