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Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System
book

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

by Z Jin
May 2014
Intermediate to advanced content levelIntermediate to advanced
550 pages
19h 34m
English
Woodhead Publishing
Content preview from Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System
Computational modeling of cell mechanics 109
where
k
1
and k
2
are elastic constants,
μ
is a viscous constant,
H
()
t
is the
Heaviside function, and
τ
is the characteristic creep time:
τ
μ
=
(
)
kk
+
kk
12
k
+
12
k
[4.20]
For cell poker experiments the response of an adherent cell to creep inden-
tation is given as (Koay et al ., 2003) (Fig. 4.9):
δ
t
F
Rk
k
kk
eH
τ
I
t
(
)
=
8
11
k
+
1
1
12
k
()
t
[4.21]
Both the linear-elastic and linear-viscoelastic solid models have been used
to determine the material properties of chondrocytes (Guilak et al ., 2000;
Trickey et al ., 2000; Leipzig and Athanasiou, 2005), endothelial cells (Ther ...
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Publisher Resources

ISBN: 9780857096616