
Computational modeling of cell mechanics 113
2004; Alexopoulos et al ., 2005; Korhonen et al ., 2006, 2008; Chahine et al .,
2007; Kim et al ., 2008, 2010) (Fig. 4.11). It has also been adapted for three-
dimensional simulations (Cao et al ., 2009; Julkunen et al ., 2009), and has
been used in concurrence with other standard models (Huang et al ., 2003).
However, some studies have shown that the biphasic model is unable to cap-
ture initial deformation characteristics of cells under compression (Leipzig
and Athanasiou, 2005).
4.8 Tensegrity model
The tensegrity model represents the cell as a mechanically stable struc-
ture, composed ...