
116 Computational Modelling of Biomechanics and Biotribology
cellular mechanics. To our knowledge, it has only been used to estimate cell
material properties, but has not been effectively employed as a whole-cell
model. Therefore, it is unable to deliver information regarding the effect of
alterations to the cell from its external mechanical environment.
4.10 Dipole polymerization model
The dipole polymerization model represents the active remolding of the
cytoskeleton as actin–myosin dipoles, which are de ned by their orientation,
as well as the magnitude of the forces that they exert. This model is used to
characterize a cell shortly ...