In the fi eld of computational neuroscience, this book is an attempt: (1)
to summarize demyelinating neuropathies such as Charcot-Marie-
Tooth Disease Type 1A (CMT1A), Chronic Infl ammatory Demyelinating
Polyneuropathy (CIDP), CIDP subtypes, Guillain-Barré Syndrome (GBS),
Multifocal Motor Neuropathy (MMN) and neuronopathies such as
Amyotrophic Lateral Sclerosis (ALS), simulated by our own models; (2)
to compare the abnormalities in their axonal excitability properties; and
(3) to explain the mechanisms underlying these abnormalities. The book,
as a huge review, contains Introduction (Chapter I), Methods (Chapter II),
Results, Discussions (Chapters III, IV) and References.
A brief description of the objects under the simulation and clinical