6 Computational Pharmacokinetics
that chapter by considering an alternative modelling approach, focussed on
the fact that the drug is transported around in the body by the blood, instead
of using volumes as the basic concepts.
Chapter 3 is about number crunching, i.e., analysis of PK data. First
we look at how integrals are estimated from the type of data obtained in
pharmacokinetics, as well as the determination of the terminal elimination rate
and how to derive a description of an absorption process through numerical
deconvolution. Thereafter we work our way through a set of real-life data,
in which two inhaled steroids are compared from a pharmacokinetics point
of view. This is an elaborate example of most aspects of what has been
discussed up to ...