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Computational Pharmacokinetics
book

Computational Pharmacokinetics

by Anders Kallen
July 2007
Intermediate to advanced content levelIntermediate to advanced
184 pages
5h 30m
English
Chapman and Hall/CRC
Content preview from Computational Pharmacokinetics
56 Computational Pharmacokinetics
FIGURE 3.8: Individual PK parameters of absorption
FIGURE 3.9: Deconvoluted absorption profiles. Thick lines are first order
processes based on F and MAT.
Numerical methods for PK parameter estimation 57
sorption process is at least close to being first order. However, for fluticasone
the deconvoluted absorption curves do not fit the thick curve well. Instead
there appear to be two phases: a relatively fast first phase, followed by a
much slower second phase. We do not investigate or discuss this observation
further.
3.6.5
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Publisher Resources

ISBN: 9781420060669