Skip to Main Content
Computational Pharmacokinetics
book

Computational Pharmacokinetics

by Anders Kallen
July 2007
Intermediate to advanced content levelIntermediate to advanced
184 pages
5h 30m
English
Chapman and Hall/CRC
Content preview from Computational Pharmacokinetics
132 Computational Pharmacokinetics
FIGURE 5.8: The integrated transfer functions H(t) through the peripheral
space
Table 5.1: Disposition parameters for the two steroids
Budesonide Fluticasone Mean Ratio
Parameter
mean 95% C.I. mean 95% C.I. ratio 95% C.I.
CL
d
(mL/min) 6513 (4709, 9009) 3655 (2622, 5094) 0.561 (0.358, 0.88)
V
ss,p
(L) 293 (270, 318) 677 (565, 812) 2.31 (1.91, 2.8)
MRT
c
(h) 0.336 (0.274, 0.413) 0.224 (0.178, 0.282) 0.665 (0.493, 0.897)
MRT
p
(h) 3.49 (3.14, 3.88) 8.24 (6.71, 10.1) 2.36 (1.89, 2.95)
MTT
p
(h) 0.749 (0.531, 1.06) 3.09 (2.24, 4.26) 4.12 (2.61, 6.5)
F
p
(%) 90.3 (88, 92.6) 97 (96.3, 97.7) 1.07 (1.05, 1.1)
K
p
10.4 (8.3, 13) 36.9 (29.2, 46.5) ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

Biomolecular and Bioanalytical Techniques

Biomolecular and Bioanalytical Techniques

Vasudevan Ramesh

Publisher Resources

ISBN: 9781420060669