Computer-aided formulation development
Ljiljana Djekic, Dragana Vasiljevic and Marija Primorac, Department of Pharmaceutical Technology Cosmetology, Faculty of Pharmacy, University of Belgrade
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and double emulsions are presented. Illustrative examples are presented to demonstrate the ability of computer-aided tools to facilitate formulation development. Various techniques, such as design of experiments and artificial neural networks, are implemented for optimization of the formulation and/or processing parameters. ...