Computer-Aided Applications in Pharmaceutical Technology

List of tables

1.1. Comparison between the traditional and QbD approaches (ICH Q8 guideline) 6

1.2. Classification of models' contribution in assuring product quality (according to ICH Q-IWG document)  9

1.3. QbD for industry and regulatory bodies  10

3.1. 2³ full factorial design  34

3.2. Determination of factor interactions  35

3.3. 2^4-1 fractional factorial design  35

3.4. Plackett-Burman design for seven factors  36

3.5. CCD for three factors  38

3.6. BBD for three factors (center point is replicated three times)  39

3.7. BBD for three factors (simplified)  39

3.8. Doehlert matrix for two variables  40

3.9. Doehlert matrix for three variables  41

3.10. Factor levels in mixture designs  43

5.1. Equivalent terms in statistics and neural ...