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Analytical methods for studying drug–biomembrane interactions

R. Pignatello,     University of Catania, Italy

Abstract:

DSC studies of the interaction between drugs or other biologically active compounds with biomembrane models has often been associated or integrated with other analytical methodologies. The information gained from various techniques can depict the different and complex elements that compose such interactions. This chapter will summarize some recent examples of successfully combining DSC with other physico-chemical methods, such as spectroscopy, chromatography, calorimetry, the Langmuir–Blodgett film technique and microscopy.

Key words

analytical methods

biomembranes

calorimetry

DSC

NMR

fluorescence spectroscopy

FRET

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