8

DSC applications: nucleic acids and membrane interactions

S. Giatrellis,     Karolinska Institute, Sweden

G. Nounesis,     National Centre for Scientific Research ‘Demokritos’, Greece

Abstract:

DSC is a non-invasive experimental technique, which, besides other numerous applications, has been extensively applied in investigating the thermodynamic properties of synthetic and biological membranes. The calorimetric profiles of phase transitions of self-organized lipid membranes can provide valuable information about membrane interactions with biomolecules, pharmaceutical agents, other membranes, etc. The scope of this chapter is to review specific applications of DSC in studying membrane– nucleic acid interactions, which have attracted scientific ...

Get Drug-Biomembrane Interaction Studies now with the O’Reilly learning platform.

O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.