Non-steroidal anti-inflammatory drugs
C. Carbone, T. Musumeci and R. Pignatello, University of Catania, Italy
Abstract:
Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.The consequent changes in the organization, fluidity and permeability of these membranes can, in some instances, be related to the pharmacological profile and toxicology of this drug class. The literature also attests the usefulness of DSC methods in studying the interaction of NSAID-loaded delivery systems ...
Get Drug-Biomembrane Interaction Studies now with the O’Reilly learning platform.
O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.
