Bone tissue regeneration

A. Bassi, J. Gough, M. Zakikhani and S. Downes,     The University of Manchester, UK


The area of bone tissue engineering is a broad field expanding at a rapid rate. Electrospinning is becoming the first choice of many researchers who are considering producing scaffolds that could be used as synthetic bone graft substitutes. This versatile, fibre-forming technique is ideal as the resulting submicrometre fibres mimic the structure of the natural extracellular matrix found in bone. Poly(ε-caprolactone) is commonly used in bone tissue engineering; the bioactivity of this polymer can be further improved through the incorporation of bioactive agents such as hydroxyapatite. Osteoporotic patients are often treated ...

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