Chapter 30DNA Microarray-Based Technologies to Genotype Single Nucleotide Polymorphisms
Jung H. Park, Ye L. Jung, Kyungmee Lee, Changyeol Lee, Batule Bhagwan and Hyun G. Park
Since the completion of the Human Genome Project (HGP), there has been predicable increase in interest concerning the types and amount of genetic diversity in the human population. Single nucleotide polymorphism (SNP) is the most abundant form of genetic variations in the human genome and has been extensively studied as genetic marker for efficient diagnosis and prognosis of various human diseases. The fundamental and standard SNP genotyping method is direct sequencing [1–3], which specifies whole base sequence in a sample genome with high accuracy. However, due to its ...
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