Chapter 43Metabolism-Combined Growth Model Construction and Its Application to Optimal Bioreactor Operation
Dong H. Jeong, Jung H. Kim and Jong M. Lee
43.1 Introduction
Bioreactor systems have a competitive edge of making high-valued products, some of which cannot be easily synthesized in conventional chemical reactors [1, 2]. With the biosynthesis industry growing, it is becoming important to increase the productivity for competitiveness. In an attempt to optimize the productivity of the bioreactor, some lab-scale researches have been focusing on genetic modification or strain screening of organisms and shown remarkable successes [3, 4].
On the other hand, operational decision making, such as design of feedstock or batch scheduling, should ...
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