Effects of Excessive Water Intake on Body-Fluid Homeostasis and the Cardiovascular System — A Computer Simulation
Y. Zhang*; W.W. Liou†; V. Gupta‡ * North Dakota State University, Fargo, ND, United States† Western Michigan University, Kalamazoo, MI, United States‡ Borgess Medical Center, Borgess Research Institute, Kalamazoo, MI, United States
Abstract
Mathematical modeling of the cardiovascular system is useful in quantifying system-level responses to external and internal perturbations, which are challenging to achieve in clinical studies. Most existing cardiovascular models are closed-loop systems and do not take into account the fluid and electrolyte exchanges and the body-fluid homeostasis. We propose a new system-level ...
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