Reconstruction of Gene Regulatory Networks Using Principal Component Analysis
X. Wu*; B. Yang*; A. Maxwell*; W. Koh*; P. Gong†; C. Zhang* * School of Computing, University of Southern Mississippi, Hattiesburg, MS, United States† Environmental Laboratory, U.S. Army Engineer Research and Development Center, Vicksburg, MS, United States
Abstract
Reconstructing complex networks of genetic interactions and identifying unknown relations among genes are very important for understanding the underlying mechanism of biological processes. Many inference methods have been proposed to reconstruct unknown gene regulatory networks (GRNs) using microarray data sets. A state space model (SSM) is a method that can be used to infer GRNs from a ...
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