Cellular Automata-Based Modeling of Three-Dimensional Multicellular Tissue Growth
B. Ben Youssef Department of Computer Engineering, King Saud University, Riyadh, Saudi Arabia
Abstract
This chapter presents the development of a computational model for the growth of multicellular tissues using discrete three-dimensional cellular automata. Different components of the model are reported where multiple types of cell populations execute persistent random walks on the computational grid, collide, aggregate, and proliferate until they reach confluence. The model allows us to study the tissue growth rates and population dynamics of different populations of migrating and proliferating mammalian cells. In this regard, simulation results ...
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