Because the reaction of urea and urease is carried out in aqueous solution, water is, of course, in excess, and the concentration of water is therefore considered constant. Let

Dividing the numerator and denominator of Equation (9-24) by *k*_{1}, we obtain a form of the *Michaelis*–*Menten equation*:

**9-25**

The final form of the rate law

The parameter *k*_{cat} is also referred to as the *turnover number*. It is the number of substrate molecules converted to product in a given time on a single-enzyme molecule when the enzyme is ...

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